Skeletal muscle relaxants (The two main categories)

Centrally acting Vs Peripherally acting


Centrally acting

Peripherally acting


↓es m. tone without loss of voluntary power

M. paralysis; voluntary power lost


In CNS: selectively inhibits polysynaptic reflexes

In CNS: NM transmission


Causes some CNS ↓

No CNS effect


Administration: oral, sometimes parenteral

Administration: Almost always IV


For: chronic spastic conditions, acute m. spasm, tetanus

For: short term purposes such as surgeries


↓: decrease

CNS: central nervous system

NM transmission: Blocks Neuromuscular transmission


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