Skeletal muscle relaxants (The two main categories)

Centrally acting Vs Peripherally acting

 

Centrally acting

Peripherally acting

1.

↓es m. tone without loss of voluntary power

M. paralysis; voluntary power lost

2.

In CNS: selectively inhibits polysynaptic reflexes

In CNS: NM transmission

3.

Causes some CNS ↓

No CNS effect

4.

Administration: oral, sometimes parenteral

Administration: Almost always IV

5.

For: chronic spastic conditions, acute m. spasm, tetanus

For: short term purposes such as surgeries

Key:

↓: decrease

CNS: central nervous system

NM transmission: Blocks Neuromuscular transmission

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

w

Connecting to %s